Back to top

 

  Center of Regenerative Medicine

 

Faculty


Select by Research Area


Cell and Tissue Engineering •
Development, Degeneration, and Aging •
Embryonic and Adult Tissue Stem Cells •
Reprogramming and Epigenetics


Select Alphabetical


A | B |C | D | E | F | G | H | I | J | K | L | M | N | O | P | Q | R | S | T | U | V | W | X | Y-Z


A
 

Rajendra Apte MD, PhD

Ophthalmology and Visual Science, Developmental Biology


Development, Degeneration, and Aging

The Apte lab studies the molecular and cellular processes underlying neovascularization and cell degeneration in the retina.


Apte Lab


B
 

Luis Batista PhD

Hematology, Developmental Biology


Embryonic and Adult Tissue Stem Cells; Development, Degeneration, and Aging

The Batista lab investigates the role of telomerase in stem cell function and regulation.


Batista Lab

     
 

Philip Bayly PhD

Mechanical Engineering and Materials Science


Cell and Tissue Engineering

The Bayly lab studies dynamic, mechanical phenomena in biomedical systems, including cortical folding and tissue mechanics in traumatic brain injury.


Bayly Lab

     
 

David Brogan MD

Orthopaedic Surgery


Development, Degeneration, and Aging; Cell and Tissue Engineering

Dr. Brogan’s research focuses on peripheral nerve injury and regeneration, using stem cells and 3D printed scaffolds as therapies.


Brogan Lab

     

C
 

W. Todd Cade PT, PhD

Physical Therapy, Medicine


Embryonic and Adult Tissue Stem Cells

The Cade lab investigates how nutritional factors influence cell behavior, and how iPSCs can be used to model human muscle diseases.


Cade Lab

     
 

Alex R. Carter, MD, PhD

Neurology


Development, Degeneration, and Aging

The Carter lab studies the mechanisms of neuroplasticity at the brain, spinal cord and peripheral levels


Carter Lab

     
 

Valeria Cavalli PhD

Neuroscience


Development, Degeneration, and Aging

The Cavalli lab studies the molecular mechanisms of PNS injury signaling and axon regrowth, and how this can inform CNS regeneration.


Cavalli Lab

     
 

Grant Challen PhD

Hematology, Oncology


Embryonic and Adult Tissue Stem Cells

The Challen lab focuses on how epigenetic marks regulate HSC self-renewal and differentiation, and how these are altered in lymphoma and leukemia.


Challen Lab

     
 

Kyunghee Choi PhD

Pathology and Immunology


Embryonic and Adult Tissue Stem Cells

The Choi lab studies the molecular mechanisms regulating vascular and hematopoietic specification and development.


Choi Lab

     
 

Matthew Ciorba MD

Internal Medicine, Gastroenterology


Embryonic and Adult Tissue Stem Cells

The Ciorba lab studies studies the roles of amino acid metabolism and microbial interactions in neoplastic and chronic inflammatory conditions of the GI tract.


Ciorba Lab

     
 

F. Session Cole MD

Pediatrics, Cell Biology and Physiology


Development, Degeneration, and Aging

The Cole lab investigates the genetic mechanisms that underlie neonatal respiratory distress syndrome.


Cole Lab

     
 

John Cooper MD, PhD

Cell Biology and Physiology, Biochemistry and Molecular Biophysics


Cell and Tissue Engineering

The Cooper lab studies the molecular basis of cell motility, including the role of motility in human disease, especially cancer.


Cooper Lab

     
 

Joseph Corbo MD, PhD

Pathology and Immunology, Genetics


Development, Degeneration, and Aging; Reprogramming and Epigenetics

The Corbo lab studies the transcriptional regulatory networks that underlie the development, evolution, and diseases of photoreceptors.


Corbo Lab

     
 

David Curiel MD, PhD

Radiation Oncology, Cancer Biology


Development, Degeneration, and Aging; Cell and Tissue Engineering

The Curiel lab studies how to engineer adenoviruses for cancer gene therapy.


Curiel Lab



D
 

Nicholas Davidson MD, DSc

Medicine, Division of Gastroenterology


Development, Degeneration, and Aging

The Davidson Lab studies the role of gatekeeper genes that regulate intestinal and hepatic lipoprotein assembly and secretion, including apoB and microsomal triglyceride transfer protein (Mttp).


Davidson Lab

     
 

Aaron DiAntonio MD, PhD

Developmental Biology


Development, Degeneration, and Aging

The DiAntonio lab studies the molecular mechanism that control axon generation, degeneration, and regeneration during development and disease.


DiAntonio Lab

     
 

John DiPersio MD, PhD

Oncology, Pediatrics, Pathology and Immunology


Embryonic and Adult Tissue Stem Cells; Cell and Tissue Engineering

The DiPersio lab studies the mechanisms underlying leukemia, hematopoietic stem cell mobilization, and graft vs. host disease.


DiPersio Lab

     
 

Abhinav Diwan, MD

Internal Medicine-Cardiology


Development, Degeneration, and Aging

The Diwan lab studies regulation of lysosome machinery in cardiometabolic diseases.


Diwan Lab


E
 

Elliot Elson PhD

Biochemistry and Molecular Biophysics


Cell and Tissue Engineering

The Elson lab studies how cells change and maintain their shapes.


Elson Lab


F
G
 

Farshid Guilak PhD

Orthopaedic Surgery


Cell and Tissue Engineering; Development, Degeneration, and Aging; Embryonic and Adult Tissue Stem Cells

The Guilak Lab is pursuing a multidisciplinary approach to investigate the etiology and pathogenesis of osteoarthritis, as a basis for the development of new pharmacologic and stem cell therapies.


Guilak Lab

     
 

David Gutmann MD, PhD

Neurology


Development, Degeneration, and Aging

The Gutmann lab studies the cellular and molecular basis underlying nervous system dysfunction in neurofibromatosis.


Gutmann Lab


H
 

James Huettner PhD

Cell Biology and Physiology


Embryonic and Adult Tissue Stem Cells; Development, Degeneration, and Aging

The Huettner lab studies how glutamate gated ion channels influence synapses and the differentiation of neurons from ES cells.


Huettner Lab

     
 

Benjamin Humphreys MD, PhD

Medicine, Renal Division


Development, Degeneration, and Aging; Embryonic and Adult Tissue Stem Cells

The Humphreys lab studies mammalian kidney injury and repair, with a focus on mechanisms of fibrogenesis.


Huphreys Lab



I
 

Shin-Ichiro Imai MD, PhD

Developmental Biology, Internal Medicine


Development, Degeneration, and Aging

The Imai lab investigates the tissues, factors, and molecular mechanisms control mammalian aging.


Imai Lab


J
 

Sanjay Jain, MD, PhD

Internal Medicine, Division of Nephrology

Pathology & Immunology


Embryonic and Adult Tissue Stem Cells; Development, Degeneration, and Aging;Cell and Tissue Engineering; and Reprogramming and Epigenetics

The Jain lab studies the molecular and cellular mechanisms that regulate maintenance, differentiation and function of kidney progenitors in normal development and disease states.


Jain Lab

     
 

Aaron Johnson PhD

Developmental Biology


Development, Degeneration, and Aging

The Johnson lab studies the development and regeneration of muscle in fly and human.


Johnson Lab

     
 

Stephen Johnson PhD

Genetics


Embryonic and Adult Tissue Stem Cells; Development, Degeneration, and Aging

The Johnson lab studies how zebrafish pigmentation and fin regeneration are controlled.


Johnson Lab


K
 

Celeste Karch PhD

Psychiatry


Cell and Tissue Engineering; Development, Degeneration, and Aging

The Karch lab studies the molecular mechanisms underlying neurodegenerative tauopathies.


     
 

Albert Kim MD, PhD

Neurological Surgery


Development, Degeneration, and Aging; Reprogramming and Epigenetics

The Kim Lab studies the cell-intrinsic molecular mechanisms governing brain cancer stem cell function, normal nervous system development, and the development of clinical surgical protocols to deliver cell-based and drug therapies for a variety of nervous system disorders.


Kim Lab

     
 

Kristen Kroll PhD

Developmental Biology


Embryonic and Adult Tissue Stem Cells; Reprogramming and Epigenetics

The Kroll lab studies the epigenetic and transcriptional regulators that control fate decisions from embryonic stem cells into the neural lineage.


Kroll Lab


L
 

Spencer Lake PhD

Mechanical Engineering & Materials Science, Biomedical Engineering, Orthopaedic Surgery


Development, Degeneration, and Aging

The Lake lab studies the biomechanics and structure-function relationships of soft tissues and how these change in injury and disease.


Lake Lab

     
 

Kory Lavine MD, PhD

Medicine, Cardiovascular Division


Development, Degeneration, and Aging

The Lavine lab studies heart development and the role of macrophages in cardiac recovery and reprogramming.


Lavine Lab

     
 

Fanxin Long PhD

Orthopedic Surgery, Developmental Biology


Embryonic and Adult Tissue Stem Cells; Development, Degeneration, and Aging

The Long lab studies the development, homeostasis, and regeneration of the skeletal system.


Long Lab


M
 

Susan Mackinnon MD

Surgery


Developing, Aging, and Degeneration

The Mackinnon lab studies peripheral nerve allotransplantation and the effect of GDNF on nerve regeneration.


Mackinnon Lab

     
 

Audrey McAlinden PhD

Orthopedic Surgery, Cell Biology and Physiology


Development, Degeneration, and Aging; Embryonic and Adult Tissue Stem Cells

The McAlinden lab studies the molecular mechanisms regulating cartilage development and maintenance.


McAlinden Lab

     
 

Robert Mecham PhD

Cell Biology and Physiology, Pediatrics, Biomedical Engineering


Cell and Tissue Engineering; Development, Degeneration, and Aging

The Mecham Lab studies how the extracellular matrix influences tissue development and regulates growth factor signaling.


Mecham Lab

     
 

Gretchen Meyer PhD

Physical Therapy


Cell and Tissue Engineering; Embryonic and Adult Tissue Stem Cells

The Meyer lab studies the effects of muscle injury at the molecular and tissue level.


Meyer Lab

     
 

Craig Micchelli PhD

Developmental Biology


Development, Degeneration, and Aging; Embryonic and Adult Tissue Stem Cells

The Micchelli lab investigates the molecular mechanisms controlling Drosophila stem cell fate decisions, and how these can inform our understanding of all stem cell systems.


Micchelli Lab

     
 

Jeff Milbrandt MD, PhD

Genetics, Pathology and Immunology, Medicine


Development, Degeneration, and Aging; Embryonic and Adult Tissue Stem Cells

The Milbrandt lab studies mechanisms that influence axonal degeneration and regeneration.


Milbrandt Lab

     
 

Timothy Miller MD, PhD

Neurology


Development, Degeneration, and Aging

The Miller lab aims to understand the mechanisms underlying neurodegeneration and to develop novel therapies for neurodegenerative diseases.


Miller Lab

     
 

Jeff Millman PhD

Endocrinology, Biomedical Engineering


Cell and Tissue Engineering; Embryonic and Adult Tissue Stem Cells

The Millman lab investigates novel stem cell technology and biomedical engineering approaches for the treatment of diabetes.


Millman Lab

     
 

Jason Mills MD, PhD

Internal Medicine, Gastroenterology, Developmental Biology


Development, Degeneration, and Aging; Embryonic and Adult Tissue Stem Cells

The Mills lab aims to understand the cellular and molecular details of adult stem cell biology in the mouse and human GI tract.


Mills Lab

     
 

Mayssa Mokalled, PhD

Developmental Biology


Development, Degeneration, and Aging

The Mokalled lab investigates mechanisms of spinal cord regeneration after injury or disease.


Mokalled Lab

     
 

Samantha Morris PhD

Genetics and Developmental Biology


Cell and Tissue Engineering; Development, Degeneration, and Aging; Embryonic and Adult Tissue Stem Cells; Reprogramming and Epigenetics

The Morris lab studies the gene regulatory networks that define cell fate. This information is applied to engineer cell identity, and to better understand cell fate decisions in development and disease.


Morris Lab

     
 

Indira Mysorekar PhD

Obstetrics and Gynecology, Pathology and Immunology


Development, Degeneration, and Aging; Embryonic and Adult Tissue Stem Cells

The Mysorekar lab aims to understand the cellular and molecular details of adult stem cell biology in the mammalian urinary bladder.


Mysorekar Lab




N
 

Jeanne Nerbonne PhD


Developmental Biology, Medicine, Biomedical Engineering


Development, Degeneration, and Aging

The Nerbonne lab studies the molecular mechanisms controlling the properties, the cell surface expression, and the function of voltage (K+) gated channels in the cardiovascular and nervous systems.


Nerbonne Lab


O
 

Regis O’Keefe MD, PhD

Orthopaedic Surgery


Embryonic and Adult Tissue Stem Cells; Development, Degeneration, and Aging

The O’Keefe lab studies skeletal development and repair, cancer, and inflammatory diseases of bone.


O'Keefe Lab

     
 

David Ornitz MD, PhD


Developmental Biology


Development, Degeneration, and Aging

The Ornitz lab investigates the functions of Fibroblast Growth Factors (FGFs), their interactions with other signaling pathways, and their role in tissue regeneration, response to injury, and cancer.


Ornitz Lab


P
 

Cecilia Pascual-Garrido, MD

Mechanical Engineering and Materials Science


Embryonic and Adult Tissue Stem Cells; Development, Degeneration and Aging

Dr. Pascual-Garrido’s lab focuses on stem cell therapies for cartilage regeneration.


Pascual-Garrido Lab

     
 

Amit Pathak PhD

Mechanical Engineering and Materials Science


Cell and Tissue Engineering; Embryonic and Adult Tissue Stem Cells

The Patak lab uses a multidisciplinary approach combining methods and concepts from biomaterials, microfluidics, molecular and cell biology, microscopy, applied mechanics, and computational modeling to investigate the ability of living cells to move through complex tissue environments.


Pathak Lab (Cellular Mechanobiology Laboratory)


Q
R
 

M. Farooq Rai PhD

Orthopaedic Surgery


Cell and Tissue Engineering; Embryonic and Adult Tissue Stem Cells; Development, Degeneration, and Aging

Dr. Rai is interested in understanding the early molecular mechanisms that orchestrate changes in knee joint after injury and lead to the development of post-traumatic osteoarthritis.


Sandell(Rai) Lab

     
 

Gwendalyn Randolph PhD

Pathology and Immunology


Development, Degeneration, and Aging

The Randolph Lab studies the development and diseases associated with monocytes, monocyte-derived cells, dendritic cells and vascular and lymphatic vessel biology.


Randolph Lab

     
 

Stacey Rentschler MD, PhD

Cardiovascular Medicine, Developmental Biology


Development, Degeneration, and Aging; Epigenetics and Reprogramming

The Rentschler lab studies the molecular mechanisms of conduction cell specification and conductive disorders in heart biology.


Rentschler Lab

     
 

Deborah Rubin MD

Gastroenterology


Development, Degeneration, and Aging

The Rubin lab studies the molecular mechanisms underlying the regulation of intestinal epithelial cell proliferation, differentiation, and carcinogenesis.


Rubin Lab

     
 

David Rudnick MD PhD

Pediatrics, Developmental Biology


Development, Degeneration, and Aging

The Rudnick lab seeks to gain an understanding of liver regeneration to improve the treatment of children with liver disease.


Rudnick Lab


S
   

 

 

Linda Sandell PhD

Orthopedic Surgery


Cell and Tissue Engineering

The Sandell lab studies how the extracellular matrix is regulated, and how the ECM controls cell phenotype and differentiation.


Sandell Lab

     
 

Mark Sands PhD

Hematology and Oncology, Genetics


Development, Degeneration, and Aging; Embryonic and Adult Stem Cells; Cell and Tissue Engineering

The Sands lab studies the underlying pathophysiology of lysosomal storage diseases and develops therapies to treat them.


Sands Lab

     
 

Tim Schedl PhD

Genetics


Development, Degeneration, and Aging; Embryonic and Adult Tissue Stem Cells

The Schedl lab investigates how stem cells choose between self renewal and differentiation and how sex determination is controlled.


Schedl Lab

     
 

Laura Schuettpelz MD, PhD

Pediatrics, Hematology and Oncology


Embryonic and Adult Tissue Stem Cells

The Schuettpelz lab studies how inflammatory signals regulate hematopoietic stem cells.


Schuettpelz Lab

     
 

Lori Setton PhD

Biomedical Engineering


Cell and Tissue Engineering; Development, Degeneration, and Aging; Embryonic and Adult Tissue Stem Cells

The Setton Lab focuses on engineering and design of novel materials and drug depots to support regeneration of tissues of the musculoskeletal system.


Setton Lab

     
 

Girdhar Sharma PhD

Radiation Oncology


Development, Degeneration, and Aging

The Sharma lab studies the molecular and epigenetic basis underlying differential radiation sensitivity.


Sharma Lab

     
 

Lavinia Sheets PhD

Otolaryngology


Development, Degeneration, and Aging

The Sheets lab uses zebrafish as a model system to understand how senory hair cells of the auditory system develop, degenerate, and regenerate. A main focus of the lab is to identify biological pathways that promote nerve regeneration and hair-cell reinnervation with the goal of providing information toward clinical regenerative therapies.


Sheets Lab

     
 

Hua Shen PhD

Orthopaedic Surgery


Cell and Tissue Engineering; Development, Degeneration, and Aging;Embryonic and Adult Tissue Stem Cells

Dr. Shen's group studies biological and mechanical factors that regulate tendon development, injury, and repair, as a basis to develop new therapeutic approaches to improve tendon healing.


Silva(Shen) Lab

     
 

Matt Silva PhD

Orthopedic Surgery, Biomedical Engineering


Development, Degeneration, and Aging

The Silva lab studies the mechanical and molecular factors that regulate loading-induced bone formation and bone injury response and repair.


Silva Lab

     
 

Lila Solnica-Krezel PhD

Developmental Biology


Development, Degeneration, and Aging; Embryonic and Adult Tissue Stem Cells

The Solnica-Krezel lab studies the cellular and molecular genetic mechanisms underlying vertebrate gastrulation in zebrafish and ES cells.


Solnica-Krezel Lab

     
 

Thaddeus Stappenbeck MD, PhD

Pathology and Immunology, Developmental Biology


Development, Degeneration, and Aging; Embryonic and Adult Tissue Stem Cells

The Stappenbeck lab investigates the interplay between the immune system and epithelial stem cells.


Stappenbeck Lab

     
 

Christopher Sturgeon PhD

Hematology, Developmental Biology


Development, Degeneration, and Aging; Embryonic and Adult Tissue Stem Cells

The Sturgeon lab studies the epigenetic and transcriptional regulators of hematopoietic stem cells.


Sturgeon Lab



T
 

Simon Tang, PhD

Orthopaedics; Biomedical Engineering; Mechanical Engineering and Materials Science


Cell and Tissue Engeineering; Development, Degeneration, and Aging

The Tang labp integrates engineering and biology approaches to investigate mechanisms of degeneration relating to bone fragility and intervertebral disc degeneration, with an emphasis in the role of advanced glycation endproducts (AGEs) and RAGE signaling on the cells and tissues of the skeletal system.


Tang Lab

     
 

Steven Teitelbaum MD

Pathology and Immunology


Development, Degeneration, and Aging

The Teitelbaum lab investigates osteoclast development, function, and pathologies.


Teitelbaum Lab


U
 

Fumihiko Urano MD, PhD

Endocrinology, Pathology and Immunology


Embryonic and Adult Tissue Stem Cells; Development, Degeneration, and Aging

The Urano lab studies the molecular mechanisms of Wolfram Syndrome and investigates potential therapies.


Urano Lab


V
W
 

Jessica Wagenseil D.Sc.

Mechanical Engineering and Materials Science


Cell and Tissue Engineering; Development, Degeneration, and Aging

The Wagenseil lab studies how mechanical stimuli regulate large artery formation and remodeling in development and disease.


Wagenseil Lab

     
 

Ting Wang PhD

Genetics


Development, Degeneration and Aging; Embryonic and Adult Tissue Stem Cells; Reprogramming and Epigenetics

The Wang lab focuses on understanding genetic and epigenetic factors that determine cell fate, including cell fate decision in normal development and differentiation, abnormal cell fate choice in cancer, and how specific cell types evolve.


Wang Lab

     
 

Mark Warchol PhD

Otolaryngology, Anatomy and Neurobiology


Development, Degeneration, and Aging

The Warchol lab studies the molecular mechanism underlying development and regeneration of sensory hair cells of the inner ear and their neurons.


Warchol Lab

     
 

Conrad Weihl, MD,PhD

Neurology


Development, Degeneration, and Aging; Cell and Tissue Engineering

The Weihl lab studies neuromuscular disorders with special emphasis on degenerative myopathies.


Weihl Lab

     
 

Matthew Wood PhD

Surgery


Development, Degeneration, and Aging; Cell and Tissue Engineering

The Wood lab studies treatment paradigms for peripheral nerve injury.


Wood Lab


XYZ
 

Qin Yang MD, PhD

Radiation Oncology


Development, Degeneration, and Aging

The Yang lab studies how tumors overcome telomere barriers to replicate indefinitely.


Yang Lab

     
 

Hiroko Yano PhD

Neurosurgery


Development, Degeneration, and Aging; Reprogramming and Epigenetics

The Yano Lab is interested in mechanisms leading to neurodegenerative diseases and brain tumors and the development of disease therapies.


Yano Lab

     
 

Andrew Yoo PhD

Developmental Biology


Development, Degeneration, and Aging; Embryonic and Adult Tissue Stem Cells; Reprogramming and Epigenetics

The Yoo lab studies how microRNAs control development, direct reprogramming, and aging in neurons.


Yoo Lab