Center of Regenerative Medicine

 

News & Events

 

 

Congratulations


Congratulations to David Ornitz and lab on their winning video of mouse lung vasculature for the 2017 FASEB BioArt competition. Link to Video.

 

 

 




Recent Publications

• Click here for 2014 Publications

 

• Click here for 2015 Publications

 

• Click here for 2016 Publications

 

• Click here for 2017 Publications

 


Loss of Dnmt3a immortalizes hematopoietic stem cells in vivo. Jeong M...Challen GA, 2018. Cell Rep, 23: 1-10.

 




Dynamic patterns of cortical expansion during folding of the preterm human brain.Garcia KE…Bayly PV, 2018, PNAS, 115: 3156-61.

 




Striatal neurons directly converted from Huntington’s Disease patients recapitulate age-associated disease phenotypes.Victor MB, Richner M, Olsen HE, Lee SW, Monteys AM, Ma C &, Huh CJ, Zhang B, Davidson BL, Yang XW, and Yoo AS. Nat. Neurosci 2018. 




Regenerative proliferation of differentiated cells by mTORC1-dependent paligenosis. Willet SG, Lewis MA, Maio Z-F, Liu D, Radyk MD, Cunningham RL, Burclaff J, Sibbel G, Lo H-Y G, Blanc V, Davidson NO, Wang Z-N, Mills JC. EMBO J, 2018.




Mechanisms of gene regulation in human embryos and pluripotent stem cells. Theunissen TW & Jaenisch R. Development 144:4496-509, 2017.





 

Intermittent fasting preserves beta-cell mass in obesity-induced diabetes via the autophagy-lysosome pathway. Liu H…Urano F, Diwan A. Autophagy 13:1952-68, 2017.

 


Environment that Enables Neuronal Subtype-Specific Reprogramming of Adult Human Fibroblasts.   Abernathy DG, Wang TYoo AS et al. Cell Stem Cell 21:322-48, 2017.


Past matrix stiffness primes epithelial cells and regulates their future collective migration through a mechanical memory.  Nasrollahi S, Walter C, Loza AJ, Schimizzi GV, Longmore GD, Pathak A.Biomaterials. 146: 146-55, 2017.


Tissue-specific DNA methylation is conserved across human, mouse, and rat, and driven by primary sequence conservation.  Zhou J, Zhang B, & Wang T et al. BMC Genomics, 18:724, 2017.


p53 mediates failure of human definitive hematopoiesis in dyskeratosis congenital.  Fok WC, Niero EL, Dege C, Brenner KA, Sturgeon CM, & Batista LFZ. Stem Cell Rep. 2017.


Human definitive hematopoietic specification from pluripotent stem cells is regulated by mesodermal expression of CDX4.  Philip Creamer J, Sturgeon CM, et al. Blood 129:2988-2992, 2017.


The SARM1 Toll/Interleukin-1 receptor domain possesses intrinsic NAD+ cleavage activity that promotes pathological axon degeneration.  Essman K, DiAntonio A, & Milbrandt J, et al. Neuron 93:1334-1343, 2017.


Therapeutic efficacy of intra-articular hyaluronan derivative and platelet-rich plasma in mice following axial tibial loading. Duan X, Sandell LJ, Chinzei N, Holguin N, Silva MJ, Schiavinato A, Rai MF. PLoS ONE 12:e0175682, 2017.