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Washington University in St. Louis - School of Medicine
Department of Developmental Biology

Andrew S. Yoo, Ph.D.

Assistant Professor

Washington University School of Medicine
Campus Box 8103
660 South Euclid Avenue
St. Louis , MO 63110
(314) 362-1811

Links

Research Interests

The general goal of my research is to understand molecular mechanisms underlying the specification of cell types and developing methods to alter the fates of cells in vitro and in vivo. We recently discovered that small RNA molecules, microRNAs, could promote generation of post-mitotic neurons by demonstrating that expression of neuron-specific microRNAs and neural factors in non-neuronal cell types could directly reprogram their cell fates into functional neurons. We currently aim to 1) develop tissue culture models of neurological diseases using patient-specific neurons and to study cell autonomous properties associated with disease states in induced neurons, and 2) to identify molecular mechanisms underlying the neurogenic activity of neuron-specific microRNAs. We will use multiple interdisciplinary approaches (including molecular genetics, genomics and biochemistry) to delineate how these microRNAs promote neuronal fates.

Selected Publications

 

For a complete list of Dr. Yoo's publications, click here

Andrew S. Yoo, Ph.D.

Assistant Professor

Washington University School of Medicine
Campus Box 8103
660 South Euclid Avenue
St. Louis , MO 63110
(314) 362-1811

Links

Other Information

Education and Training

  • 2011 - Postdoctoral fellow, Stanford University, CA, Chromatin biology and cell fate reprogramming
  • 2005 - Ph.D. Columbia University, NY, Cellular, Molecular and Biophysical Studies
  • 1998 - M.Sc. University of British Columbia, Vancouver, BC, Canada, Experimental Medicine (Neurology)
  • 1995 - B.Sc. McGill University, Montreal, PQ, Canada, Physiology (with focus on Neurophysiology)

Academic Positions

  • August 2011 - present - Assistant Professor, Department Developmental Biology, Washington University School of Medicine

Honors and Awards

  • Presidential Early Career Award for Scientist and Engineers (PECASE), 2013
  • NIH Director’s New Innovator Award, 2012-2017
  • Ellison Medical Foundation New Investigator in Aging Award, 2012-2016
  • Mallinckrodt Foundation New Investigator Award, 2011-2013           
  • Helen Hay Whitney Foundation Fellowship, 2007-2010
  • Natural Sciences and Engineering Research Council of Canada (NSERC) Postgraduate Award (for tenure at universities outside Canada), 2001-2003
  • Honors in Neurophysiology, McGill University, 1995