Top
Washington University in St. Louis - School of Medicine
Department of Developmental Biology

Zebrafish

Kelly Monk, Ph.D.

Lila Solnica-Krezel, Ph.D.

 

The zebrafish is one of the premier model organisms for the genetic analysis of early vertebrate development, organogenesis and regeneration. It has also quickly established itself as an outstanding system in which to model human birth defects and diseases, including cancer. Studies performed on zebrafish have greatly enriched our understanding of the molecular and cellular mechanisms underlying cell fate decisions and morphogenetic processes. Thus, studies of zebrafish mutants offer the dissection of disease mechanisms, and may also lead to novel regenerative therapies.  Dr. Kelly Monk’s laboratory employs the zebrafish model to study development, maintenance and regeneration of myelin. Dr. Lila Solnica-Krezel’s laboratory is focused on cell interactions and movements that establish the animal body plan during gastrulation. Zebrafish research at WUSM is facilitated by the most modern Zebrafish Facility in the world and collaborative interactions with other researchers of the WU Zebrafish Consortium.

Upcoming Events

Nov 26

Mayssa Mokalled, Ph.D.

Department of Developmental Biology Seminar Series

Assistant Professor Department of Developmental Biology Washington University School…

Nov 28

Jasmin Sponagel (Josh Rubin Lab)/ Shanshan Song (Aaron Johnson lab)

RAD Research Forum Series

12:00 pm, Needleman Library

Dec 3

William Mair, Ph.D.

Department of Developmental Biology Seminar Series

Associate Professor of Genetics and Complex Diseases Department of…

See all upcoming events

Faculty News

  • Dr. David Ornitz October 2018 Publication

    Congratulations to Dr. David Ornitz's Lab on their recent publication! Impaired tumor growth and angiogenesis in mice heterozygous for Vegfr2 (Flk1). Oladipupo SS, Kabir…

  • Dr. Stacey Rentschler’s October 2018 Publication

    Congratulations to Dr. Stacey Rentschler's Lab on their recent publication! Differential Wnt-mediated programming and arrhythmogenesis in right versus left ventricles. Li G, Khandekar A,…

See all faculty news