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Washington University in St. Louis - School of Medicine
Department of Developmental Biology

Zebrafish

Kelly Monk, Ph.D.

Lila Solnica-Krezel, Ph.D.

 

The zebrafish is one of the premier model organisms for the genetic analysis of early vertebrate development, organogenesis and regeneration. It has also quickly established itself as an outstanding system in which to model human birth defects and diseases, including cancer. Studies performed on zebrafish have greatly enriched our understanding of the molecular and cellular mechanisms underlying cell fate decisions and morphogenetic processes. Thus, studies of zebrafish mutants offer the dissection of disease mechanisms, and may also lead to novel regenerative therapies.  Dr. Kelly Monk’s laboratory employs the zebrafish model to study development, maintenance and regeneration of myelin. Dr. Lila Solnica-Krezel’s laboratory is focused on cell interactions and movements that establish the animal body plan during gastrulation. Zebrafish research at WUSM is facilitated by the most modern Zebrafish Facility in the world and collaborative interactions with other researchers of the WU Zebrafish Consortium.

Upcoming Events

Dec 13

Rich Li (Stacey Rentschler Lab) and Sergej Djuranovic

Development and Regenerative Biology / Cell-Cell Interactions in Cancer Research Forum (Wednesday)

Dec 18
Jan 8

Marianne Bronner, Ph.D.

Department of Developmental Biology Seminar Series

Albert Billings Ruddock Professor of Biology California Institute of…

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Faculty News

  • Dr. Greg Grant’s November 2017 Publication

    Congratulations to Dr. Greg Grant's Lab on their recent publication! Regulatory Mechanism of Mycobacterium tuberculosis Phosphoserine Phosphatase SerB2. Grant GA. Biochemistry. 2017 Nov 22.

  • Dr. Zach Pincus’s November 2017 Publication

    Congratulations to Dr. Zach Pincus's Lab on their recent Publication! A microRNA feedback loop regulates global microRNA abundance during aging. Inukai S, Pincus Z,…

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