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Washington University in St. Louis - School of Medicine
Department of Developmental Biology

Zebrafish

Kelly Monk, Ph.D.

Lila Solnica-Krezel, Ph.D.

 

The zebrafish is one of the premier model organisms for the genetic analysis of early vertebrate development, organogenesis and regeneration. It has also quickly established itself as an outstanding system in which to model human birth defects and diseases, including cancer. Studies performed on zebrafish have greatly enriched our understanding of the molecular and cellular mechanisms underlying cell fate decisions and morphogenetic processes. Thus, studies of zebrafish mutants offer the dissection of disease mechanisms, and may also lead to novel regenerative therapies.  Dr. Kelly Monk’s laboratory employs the zebrafish model to study development, maintenance and regeneration of myelin. Dr. Lila Solnica-Krezel’s laboratory is focused on cell interactions and movements that establish the animal body plan during gastrulation. Zebrafish research at WUSM is facilitated by the most modern Zebrafish Facility in the world and collaborative interactions with other researchers of the WU Zebrafish Consortium.

Upcoming Events

Oct 23

Dennis Kim, M.D., Ph,D.

Department of Developmental Biology Seminar Series

 Dennis Kim, M.D., Ph,D. Ivan R.…

Oct 24

Chuner Guo

RAD Journal Club

DBBS Graduate Research Asst Dr. Samantha Morris's Lab …

Oct 25

Chuner Guo (Samantha Morris Lab) and Anna Ballard (Novack Lab)

Development and Regenerative Biology / Cell-Cell Interactions in Cancer Research Forum (Wednesday)

See all upcoming events

Faculty News

  • Dr. Kelly Monk’s August 2017 Publication

    Congratulations to Dr. Kelly Monk's Lab on their recent publication! Whole Genome Sequencing-Based Mapping and Candidate Identification of Mutations from Fixed Zebrafish Tissue. Sanchez…

  • Dr. Stacey Rentschler’s August 2017 Publication

    Congratulations to Dr. Stacey Rentschler's Lab on their recent publication! Transient Notch Activation Induces Long-Term Gene Expression Changes Leading to Sick Sinus Syndrome in…

See all faculty news