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Washington University in St. Louis - School of Medicine
Department of Developmental Biology

Zebrafish

Kelly Monk, Ph.D.

Lila Solnica-Krezel, Ph.D.

 

The zebrafish is one of the premier model organisms for the genetic analysis of early vertebrate development, organogenesis and regeneration. It has also quickly established itself as an outstanding system in which to model human birth defects and diseases, including cancer. Studies performed on zebrafish have greatly enriched our understanding of the molecular and cellular mechanisms underlying cell fate decisions and morphogenetic processes. Thus, studies of zebrafish mutants offer the dissection of disease mechanisms, and may also lead to novel regenerative therapies.  Dr. Kelly Monk’s laboratory employs the zebrafish model to study development, maintenance and regeneration of myelin. Dr. Lila Solnica-Krezel’s laboratory is focused on cell interactions and movements that establish the animal body plan during gastrulation. Zebrafish research at WUSM is facilitated by the most modern Zebrafish Facility in the world and collaborative interactions with other researchers of the WU Zebrafish Consortium.

Upcoming Events

Sep 18

Lavinia Sheets. Ph.D.

Department of Developmental Biology Seminar Series

Dr. Lavinia Sheets Asst Prof Department of Otolaryngology 12:00 pm,…

Sep 25

Lawrence Lum, Ph.D.

Department of Developmental Biology Seminar Series

 Lawrence Lum, Ph.D. Pfizer 12:00 pm, Needleman Library

Sep 27

Rich Li (Stacey Rentschler Lab)

Development and Regenerative Biology / Cell-Cell Interactions in Cancer Research Forum (Wednesday)

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Faculty News

  • Dr. Samantha Morris’s June 2017 Publication

    Engineering cell identity: establishing new gene regulatory and chromatin landscapes. Guo C, Morris SA. Curr Opin Genet Dev. 2017 Jun 28;46:50-57.

  • Dr. Doug Covey’s June 2017 Publication

    Photoaffinity labeling with cholesterol analogues precisely maps a cholesterol-binding site in voltage-dependent anion channel-1. Budelier MM, Cheng WWL, Bergdoll L, Chen ZW, Janetka JW, Abramson…

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