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Washington University in St. Louis - School of Medicine
Department of Developmental Biology

Human Cells

Kris Kroll, Ph.D.

Jeanne Nerbonne, Ph.D.

Lila Solnica-Krezel, Ph.D.

Andrew Yoo, Ph.D.

 

Recent technical breakthroughs in engineering human somatic cells to induce pluripotent stem cells or directly convert into another cell type offer unprecedented opportunities for regenerative medicine.  These relatively novel research tools, commonly referred to as cell fate reprogramming, allow derivation of individual-specific stem cells or differentiated cell types geared towards developing disease models of inherited diseases or cell replacement-based therapeutic approaches.  Additionally, human embryonic stem cell lines that have been approved as experimental tools can be used to study genetic pathways underlying cellular differentiations.  Towards these goals, faculties in the department use human cells to study genetic pathways that govern cellular differentiation, develop experimental protocols for deriving various cell types for disease modeling or functional rescue of cellular functions lost in diseased states.  

Upcoming Events

Oct 24

Chuner Guo

RAD Journal Club

DBBS Graduate Research Asst Dr. Samantha Morris's Lab …

Oct 25

Chuner Guo (Samantha Morris Lab) and Anna Ballard (Novack Lab)

Development and Regenerative Biology / Cell-Cell Interactions in Cancer Research Forum (Wednesday)

Oct 30

Erika Sasaki, Ph.D.

Department of Developmental Biology Seminar Series

Department Head Department of Applied Developmental Biology, Central Institute…

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Faculty News

  • Dr. Kelly Monk’s August 2017 Publication

    Congratulations to Dr. Kelly Monk's Lab on their recent publication! Whole Genome Sequencing-Based Mapping and Candidate Identification of Mutations from Fixed Zebrafish Tissue. Sanchez…

  • Dr. Stacey Rentschler’s August 2017 Publication

    Congratulations to Dr. Stacey Rentschler's Lab on their recent publication! Transient Notch Activation Induces Long-Term Gene Expression Changes Leading to Sick Sinus Syndrome in…

See all faculty news