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Washington University in St. Louis - School of Medicine
Department of Developmental Biology

Human Cells

Kris Kroll, Ph.D.

Jeanne Nerbonne, Ph.D.

Lila Solnica-Krezel, Ph.D.

Andrew Yoo, Ph.D.

 

Recent technical breakthroughs in engineering human somatic cells to induce pluripotent stem cells or directly convert into another cell type offer unprecedented opportunities for regenerative medicine.  These relatively novel research tools, commonly referred to as cell fate reprogramming, allow derivation of individual-specific stem cells or differentiated cell types geared towards developing disease models of inherited diseases or cell replacement-based therapeutic approaches.  Additionally, human embryonic stem cell lines that have been approved as experimental tools can be used to study genetic pathways underlying cellular differentiations.  Towards these goals, faculties in the department use human cells to study genetic pathways that govern cellular differentiation, develop experimental protocols for deriving various cell types for disease modeling or functional rescue of cellular functions lost in diseased states.  

Upcoming Events

Nov 26

Mayssa Mokalled, Ph.D.

Department of Developmental Biology Seminar Series

Assistant Professor Department of Developmental Biology Washington University School…

Nov 28

Jasmin Sponagel (Josh Rubin Lab)/ Shanshan Song (Aaron Johnson lab)

RAD Research Forum Series

12:00 pm, Needleman Library

Dec 3

William Mair, Ph.D.

Department of Developmental Biology Seminar Series

Associate Professor of Genetics and Complex Diseases Department of…

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Faculty News

  • Dr. David Ornitz October 2018 Publication

    Congratulations to Dr. David Ornitz's Lab on their recent publication! Impaired tumor growth and angiogenesis in mice heterozygous for Vegfr2 (Flk1). Oladipupo SS, Kabir…

  • Dr. Stacey Rentschler’s October 2018 Publication

    Congratulations to Dr. Stacey Rentschler's Lab on their recent publication! Differential Wnt-mediated programming and arrhythmogenesis in right versus left ventricles. Li G, Khandekar A,…

See all faculty news