Raphael
Kopan, Ph.D.
Professor
Department of Molecular Biology and Pharmacology
and the Department of Medicine (Division of Dermatology)
Washington University
3600 Cancer Research Building
Box 8103
660 South Euclid
St. Louis, MO 63110
Office phone: (314) 747-5520
Lab phone: (314) 747-5521; (314) 747-5522
Fax: (314) 747-7058
kopan@wustl.edu
ftp://kopanftp@soxsftp.wustl.edu
Downloadable Teaching Aides:
Selected Reviews and Materials:
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Dilip Chandu, Stacey S. Huppert and Raphael Kopan: Analysis of transmembrane domain mutants is consistent with sequential cleavage of Notch by c-secretase Journal of Neurochemistry 2006, 96, 228–235 Click here to open PDF File
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Kopan R and Turner DL: The Notch pathway: democracy and aristocracy in the selection of cell fate.ÊCurrent Opinion in Neurobiology 1996;6:594-601.
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Kopan R and Cagan, R.: Notch at the cutting edge (comment). Trends in Genetics, 1997:13;465-467.
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Good Things Must Come to an End: How Is Notch Signaling Turned off? Kopan R.Ê See the manuscript at: http://www.stke.org/cgi/content/full/OC_sigtrans;1999/9/pe1.
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Mumm JS, and Kopan R: Notch Signaling: From the outside in. Developmental Biology, 2000: 228,151-165. 8. Click here to see figures and legends from the manuscript.
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Kopan R and Goate A: A common enzyme connects Notch signaling with Alzheimer disease. Genes and Development. 2000; 14: 2799-2806. See figures from the manuscript: http://devbio.wustl.edu/kopanlab/comenz02.htm.
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List of Publications and other information available at the Molecular Biology and Pharmacology Website: http://devbio.wustl.edu/kopan.htm and also at the Dermatology Website: http://dermatology.wustl.edu/faculty/kopan.htm
Popular Constructs:
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All our expression studies are performed with pCS2 vectors. This is the number one request from our lab and a .pdf copy can be viewed with Adobe Acrobat Reader.
Current Lab Members:
