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Washington University in St. Louis - School of Medicine
Department of Developmental Biology

Research News

  • Dr. Kelly Monk December Publication

    Adhesion GPCRs as Novel Actors in Neural and Glial Cell Functions: From Synaptogenesis to Myelination. Sigoillot SM, Monk KR, Piao X, Selimi F, Harty BL.…

  • Dr. Shin Imai December Publication

    Long-Term Administration of Nicotinamide Mononucleotide Mitigates Age-Associated Physiological Decline in Mice. Mills KF, Yoshida S, Stein LR, Grozio A, Kubota S, Sasaki Y, Redpath P,…

  • Dr. David Ornitz December Publication

    Elevated Fibroblast Growth Factor Signaling Is Critical for the Pathogenesis of the Dwarfism in Evc2/Limbin Mutant Mice. Zhang H, Kamiya N, Tsuji T, Takeda…

  • Dr. Douglas Covey November Publication

    A novel mechanism of non-feminizing estrogens in neuroprotection. Engler-Chiurazzi EB, Covey DF, Simpkins JW. Exp Gerontol. 2016 Nov 3. pii: S0531-5565(16)30465-X.

  • Dr. Kelly Monk December Publication

    Gpr126/Adgrg6 Has Schwann Cell Autonomous and Nonautonomous Functions in Peripheral Nerve Injury and Repair. Mogha A, Harty BL, Carlin D, Joseph J, Sanchez NE,…

  • Dr. Kristen Kroll November Publication

    Gene regulatory networks in neural cell fate acquisition from genome-wide chromatin association of Geminin and Zic1. Sankar S, Yellajoshyula D, Zhang B, Teets B, Rockweiler…

  • Dr. David Ornitz December Publication

    Achondroplasia: Development, Pathogenesis, and Therapy. Ornitz DM, Legeai-Mallet L. Dev Dyn. 2016 Dec 17.

  • Dr. Kelly Monk December Publication

    Adhesion GPCRs as Novel Actors in Neural and Glial Cell Functions: From Synaptogenesis to Myelination. Sigoillot SM, Monk KR, Piao X, Selimi F, Harty BL.…

  • Dr. Kelly Monk December Publication

    Adhesion GPCRs as a Putative Class of Metabotropic Mechanosensors. Scholz N, Monk KR, Kittel RJ, Langenhan T. Handb Exp Pharmacol. 2016;234:221-247.

  • Dr. Doug Covey November Publication

    Fatty acid synthesis configures the plasma membrane for inflammation in diabetes. Wei X, Song H, Yin L, Rizzo MG, Sidhu R, Covey DF, Ory DS,…

  • Dr. Lila Solnica-Krezel November Publication

    The Colonic Crypt Protects Stem Cells from Microbiota-Derived Metabolites. Kaiko GE, Ryu SH, Koues OI, Collins PL, Solnica-Krezel L, Pearce EJ, Pearce EL, Oltz EM,…

  • Dr. Jeanne Nerbonne November Publication

    Potassium currents in the heart: Functional roles in repolarization, arrhythmia and therapeutics. Chiamvimonvat N, Chen-Izu Y, Clancy CE, Deschenes I, Dobrev D, Heijman J, Izu…

  • Dr. Kelly Monk November Publication

    G Protein-Coupled Receptors in Myelinating Glia. Mogha A, D'Rozario M, Monk KR. Trends Pharmacol Sci. 2016 Nov;37(11):977-987.

  • Dr. Aaron DiAntonio October Publication

    Prevention of vincristine-induced peripheral neuropathy by genetic deletion of SARM1 in mice. Geisler S, Doan RA, Strickland A, Huang X, Milbrandt J, DiAntonio A. Brain. 2016…

  • Dr. Doug Covey October Publication

    Structure-activity studies of non-steroid analogues structurally-related to neuroprotective estrogens. Qian M, Engler-Chiurazzi EB, Lewis SE, Rath NP, Simpkins JW, Covey DF. Org Biomol Chem. 2016 Oct 18;14(41):979…

  • Dr. Doug Covey October Publication

    Cholesterol activates the G-protein coupled receptor Smoothened to promote morphogenetic signaling. Luchetti G, Sircar R, Kong JH, Nachtergaele S, Sagner A, Byrne EF, Covey DF,…

  • Dr. Zach Pincus October Publication

    Extended Twilight among Isogenic C. elegans Causes a Disproportionate Scaling between Lifespan and Health. Zhang WB, Sinha DB, Pittman WE, Hvatum E, Stroustrup N, Pincus…

  • Dr. David Ornitz October Publication

    An S116R Phosphorylation Site Mutation in Human Fibroblast Growth Factor-1 Differentially Affects Mitogenic and Glucose-Lowering Activities. Xia X, Kumru OS, Blaber SI, Middaugh CR,…

  • Dr. Aaron DiAntonio October Publication

    NMNAT1 inhibits axon degeneration via blockade of SARM1-mediated NAD+ depletion. Sasaki Y, Nakagawa T, Mao X, DiAntonio A, Milbrandt J. Elife. 2016 Oct 13;5.

  • Drs. Jeanne Nerbonne and Stacey Rentschler New Publication

    Notch-Mediated Epigenetic Regulation of Voltage-Gated Potassium Currents. Khandekar A, Springer S, Wang W, Hicks S, Weinheimer CJ, Diaz-Trelles R, Nerbonne JM, Rentschler S. Circ Res. 2016…

  • Dr. Doug Covey December Publication

    TSPO activation modulates the effects of high pressure in a rat ex vivo glaucoma model. Ishikawa M, Yoshitomi T, Covey DF, Zorumski CF, Izumi Y.…

  • Dr. Kelly Monk November Publication

    G Protein-Coupled Receptors in Myelinating Glia. Mogha A, D'Rozario M, Monk KR.Trends Pharmacol Sci. 2016 Nov;37(11):977-987.

  • Dr. Andrew Yoo September Publication

    Maintenance of age in human neurons generated by microRNA-based neuronal conversion of fibroblasts. Huh CJ, Zhang B, Victor MB, Dahiya S, Batista LF, Horvath S,…

  • Dr. Kelly Monk September Publication

    Structural Basis for Regulation of GPR56/ADGRG1 by Its Alternatively Spliced Extracellular Domains. Salzman GS, Ackerman SD, Ding C, Koide A, Leon K, Luo R,…

  • Dr. Shim Imai September Publication

    NAMPT-Mediated NAD(+) Biosynthesis Is Essential for Vision In Mice. Lin JB, Kubota S, Ban N, Yoshida M, Santeford A, Sene A, Nakamura R, Zapata N,…

  • Dr. Kelly Monk August Publication

    The prion protein is an agonistic ligand of the G protein-coupled receptor Adgrg6. Küffer A, Lakkaraju AK, Mogha A, Petersen SC, Airich K,…

  • Dr. Kelly Monk September Publication

    Adhesion G protein-coupled receptors in nervous system development and disease. Langenhan T, Piao X, Monk KR. Nat Rev Neurosci. 2016 Sep;17(9):550-61.

  • Dr. Samantha Morris August Publication

    Direct lineage reprogramming via pioneer factors; a detour through developmental gene regulatory networks. Morris SA. Development. 2016 Aug 1;143(15):2696-705.

  • Dr. Alison Snyder-Warwick’s New July Publication

    Axonal Growth Arrests After an Increased Accumulation of Schwann Cells Expressing Senescence Markers and Stromal Cells in Acellular Nerve Allografts. Poppler LH, Ee X, Schellhardt…

  • Dr. Doug Covey’s New July Publication

    Structural basis of Smoothened regulation by its extracellular domains. Byrne EF, Sircar R, Miller PS, Hedger G, Luchetti G, Nachtergaele S, Tully MD, Mydock-McGrane L,…

  • Dr. Aaron DiAntonio’s June Publication

    An evolutionarily conserved mechanism for cAMP elicited axonal regeneration involves direct activation of the dual leucine zipper kinase DLK. Hao Y, Frey E, Yoon C,…

  • Dr. Zach Pincus June Publication

    High-throughput screening in the C. elegans nervous system. Kinser HE, Pincus Z. Mol Cell Neurosci. 2016 Jun 3.

  • Dr. Kristen Kroll’s New June Publication

    Complexities of X chromosome inactivation status in female human induced pluripotent stem cells-a brief review and scientific update for autism research. Dandulakis MG, Meganathan K,…

  • Dr. Lila Solnica-Krezel’s New June Publication

    The Colonic Crypt Protects Stem Cells from Microbiota-Derived Metabolites. Kaiko GE, Ryu SH, Koues OI, Collins PL, Solnica-Krezel L, Pearce EJ, Pearce EL, Oltz EM,…

  • Dr. Kerry Kornfeld’s New Publication

    Insights into zinc and cadmium biology in the nematode Caenorhabditis elegans. Dietrich N, Tan CH, Cubillas C, Earley BJ, Kornfeld K. Arch Biochem Biophys. 2016 May 31.

  • Dr. Doug Covey’s New Publication

    Development of a bile acid-based newborn screen for Niemann-Pick disease type C. Jiang X, Sidhu R, Mydock-McGrane L, Hsu FF, Covey DF, Scherrer DE, Earley…

  • Dr. Solnica-Krezel’s New Publication

    Dachsous1b cadherin regulates actin and microtubule cytoskeleton during early zebrafish embryogenesis. Li-Villarreal N, Forbes MM, Loza AJ, Chen J, Ma T, Helde K, Moens…

  • Dr. Jeanne Nerbonne’s New Publication

    IA Channels Encoded by Kv1.4 and Kv4.2 Regulate Circadian Period of PER2 Expression in the Suprachiasmatic Nucleus. Granados-Fuentes D, Hermanstyne TO, Carrasquillo Y, Nerbonne JM,…

  • Dr. David Ornitz’s New Publication

    Fibroblast growth factor signaling in skeletal development and disease. Ornitz DM, Marie PJ. Genes Dev. 2015 Jul 15;29(14):1463-86.

  • Dr. Snyder-Warwick’s New Publication

    Side-To-Side Nerve Bridges Support Donor Axon Regeneration Into Chronically Denervated Nerves and Are Associated With Characteristic Changes in Schwann Cell Phenotype.Hendry JM, Alvarez-Veronesi MC,…

  • Dr. Snyder-Warwick’s New Publication

    Maxillomandibular Fixation by Plastic Surgeons: Cost Analysis and Utilization of Resources. Farber SJ, Snyder-Warwick AK, Skolnick GB, Woo AS, Patel KB. Ann Plast Surg. 2015 Jul 23.

  • Dr. Lila Solnica-Krezel’s Recent Publication

    A dynamic intracellular distribution of Vangl2 accompanies cell polarization during zebrafish gastrulation. Roszko I, S Sepich D, Jessen JR, Chandrasekhar A, Solnica-Krezel L. Development. 2015 Jul 15;142(14):250…

Faculty News

  • Dr. Kelly Monk December Publication

    Adhesion GPCRs as Novel Actors in Neural and Glial Cell Functions: From Synaptogenesis to Myelination. Sigoillot SM, Monk KR, Piao X, Selimi F, Harty BL.…

  • Dr. Shin Imai December Publication

    Long-Term Administration of Nicotinamide Mononucleotide Mitigates Age-Associated Physiological Decline in Mice. Mills KF, Yoshida S, Stein LR, Grozio A, Kubota S, Sasaki Y, Redpath P,…

See all faculty news