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Washington University in St. Louis - School of Medicine
Department of Developmental Biology

Research News

  • Dr. Lila Solnica-Krezel’s February 2017 Publication

    Stat3/Cdc25a-dependent cell proliferation promotes embryonic axis extension during zebrafish gastrulation. Liu Y, Sepich DS, Solnica-Krezel L. PLoS Genet. 2017 Feb 21;13(2):e1006564.

  • Dr. Doug Covey’s February Publication

    Click Chemistry Reagent for Identification of Sites of Covalent Ligand Incorporation in Integral Membrane Proteins. Budelier MM, Cheng WW, Bergdoll L, Chen ZW, Abramson J,…

  • Dr. Alison Snyder-Warwick’s February 2017 Publication

    Worldwide Testing of the eFACE Facial Nerve Clinician-Graded Scale. Banks CA, Jowett N, Azizzadeh B, Beurskens C, Bhama P, Borschel G, Coombs C, Coulson S,…

  • Dr. Gregory Grant’s February 2017 Publication

    Modification of Cysteine. Grant GA. Curr Protoc Protein Sci. 2017 Feb 2;87:15.1.1-15.1.23. To view publication, click here      

  • Dr. Aaron DiAntonio’s New March 2017 Publication

    The SARM1 Toll/Interleukin-1 Receptor Domain Possesses Intrinsic NAD+ Cleavage Activity that Promotes Pathological Axonal Degeneration. Essuman K, Summers DW, Sasaki Y, Mao X, DiAntonio…

  • Dr. Lila Solnica-Krezel’s New March 2017 Publication

    Imaging early embryonic calcium activity with GCaMP6s transgenic zebrafish. Chen J, Xia L, Bruchas MR, Solnica-Krezel L. Dev Biol. 2017 Mar 18. pii: S0012-1606(17)30174-4.

  • Dr. Doug Covey’s March 2017 Publication

    Synthesis of side-chain oxysterols and their enantiomers through cross-metathesis reactions of Δ22 steroids. Brownholland DP, Covey DF. Steroids. 2017 May;121:22-31.

  • Dr. Kerry Kornfeld’s January 2017 Publication

    The Nuclear Receptor HIZR-1 Uses Zinc as a Ligand to Mediate Homeostasis in Response to High Zinc. Warnhoff K, Roh HC, Kocsisova Z, Tan CH,…

  • Dr. Alison Snyder-Warwick’s February 2017 Publication

    Surgical Treatment of Neuromas Improves Patient-Reported Pain, Depression, and Quality of Life. Domeshek LF, Krauss EM, Snyder-Warwick AK, Laurido-Soto O, Hasak JM, Skolnick GB, Novak…

  • Dr. Alison Snyder-Warwick’s January 2017 Publication

    Photographic Standards for Patients With Facial Palsy and Recommendations by Members of the Sir Charles Bell Society. Santosa KB, Fattah A, Gavilán J,…

  • Dr. Aaron DiAntonio’s January 2017 Publication

    MAPK signaling promotes axonal degeneration by speeding the turnover of the axonal maintenance factor NMNAT2. Walker LJ, Summers DW, Sasaki Y, Brace EJ, Milbrandt J,…

  • Dr. Jeanne Nerbonne’s January 2017 Publication

    Early remodeling of repolarizing K+ currents in the αMHC403/+ mouse model of familial hypertrophic cardiomyopathy. Hueneke R, Adenwala A, Mellor RL, Seidman JG, Seidman…

  • Dr. Kelly Monk’s January 2017 New Publication

    Analysis of myelinated axon formation in zebrafish. D'Rozario M, Monk KR, Petersen SC. Methods Cell Biol. 2017;138:383-414.

  • Dr. Alison Snyder-Warwick’s December Publication

    Robust Axonal Regeneration in a Mouse Vascularized Composite Allotransplant Model Undergoing Delayed Tissue Rejection. Yan Y, Wood MD, Moore AM, Snyder-Warwick AK, Hunter DA, Newton…

  • Dr. Kelly Monk December Publication

    Adhesion GPCRs as Novel Actors in Neural and Glial Cell Functions: From Synaptogenesis to Myelination. Sigoillot SM, Monk KR, Piao X, Selimi F, Harty BL.…

  • Dr. Shin Imai December Publication

    Long-Term Administration of Nicotinamide Mononucleotide Mitigates Age-Associated Physiological Decline in Mice. Mills KF, Yoshida S, Stein LR, Grozio A, Kubota S, Sasaki Y, Redpath P,…

  • Dr. David Ornitz December Publication

    Elevated Fibroblast Growth Factor Signaling Is Critical for the Pathogenesis of the Dwarfism in Evc2/Limbin Mutant Mice. Zhang H, Kamiya N, Tsuji T, Takeda…

  • Dr. Douglas Covey November Publication

    A novel mechanism of non-feminizing estrogens in neuroprotection. Engler-Chiurazzi EB, Covey DF, Simpkins JW. Exp Gerontol. 2016 Nov 3. pii: S0531-5565(16)30465-X.

  • Dr. Kelly Monk December Publication

    Gpr126/Adgrg6 Has Schwann Cell Autonomous and Nonautonomous Functions in Peripheral Nerve Injury and Repair. Mogha A, Harty BL, Carlin D, Joseph J, Sanchez NE,…

  • Dr. Kristen Kroll November Publication

    Gene regulatory networks in neural cell fate acquisition from genome-wide chromatin association of Geminin and Zic1. Sankar S, Yellajoshyula D, Zhang B, Teets B, Rockweiler…

  • Dr. David Ornitz December Publication

    Achondroplasia: Development, Pathogenesis, and Therapy. Ornitz DM, Legeai-Mallet L. Dev Dyn. 2016 Dec 17.

  • Dr. Kelly Monk December Publication

    Adhesion GPCRs as Novel Actors in Neural and Glial Cell Functions: From Synaptogenesis to Myelination. Sigoillot SM, Monk KR, Piao X, Selimi F, Harty BL.…

  • Dr. Kelly Monk December Publication

    Adhesion GPCRs as a Putative Class of Metabotropic Mechanosensors. Scholz N, Monk KR, Kittel RJ, Langenhan T. Handb Exp Pharmacol. 2016;234:221-247.

  • Dr. Doug Covey November Publication

    Fatty acid synthesis configures the plasma membrane for inflammation in diabetes. Wei X, Song H, Yin L, Rizzo MG, Sidhu R, Covey DF, Ory DS,…

  • Dr. Lila Solnica-Krezel November Publication

    The Colonic Crypt Protects Stem Cells from Microbiota-Derived Metabolites. Kaiko GE, Ryu SH, Koues OI, Collins PL, Solnica-Krezel L, Pearce EJ, Pearce EL, Oltz EM,…

  • Dr. Jeanne Nerbonne November Publication

    Potassium currents in the heart: Functional roles in repolarization, arrhythmia and therapeutics. Chiamvimonvat N, Chen-Izu Y, Clancy CE, Deschenes I, Dobrev D, Heijman J, Izu…

  • Dr. Kelly Monk November Publication

    G Protein-Coupled Receptors in Myelinating Glia. Mogha A, D'Rozario M, Monk KR. Trends Pharmacol Sci. 2016 Nov;37(11):977-987.

  • Dr. Aaron DiAntonio October Publication

    Prevention of vincristine-induced peripheral neuropathy by genetic deletion of SARM1 in mice. Geisler S, Doan RA, Strickland A, Huang X, Milbrandt J, DiAntonio A. Brain. 2016…

  • Dr. Doug Covey October Publication

    Structure-activity studies of non-steroid analogues structurally-related to neuroprotective estrogens. Qian M, Engler-Chiurazzi EB, Lewis SE, Rath NP, Simpkins JW, Covey DF. Org Biomol Chem. 2016 Oct 18;14(41):979…

  • Dr. Doug Covey October Publication

    Cholesterol activates the G-protein coupled receptor Smoothened to promote morphogenetic signaling. Luchetti G, Sircar R, Kong JH, Nachtergaele S, Sagner A, Byrne EF, Covey DF,…

  • Dr. Zach Pincus October Publication

    Extended Twilight among Isogenic C. elegans Causes a Disproportionate Scaling between Lifespan and Health. Zhang WB, Sinha DB, Pittman WE, Hvatum E, Stroustrup N, Pincus…

  • Dr. David Ornitz October Publication

    An S116R Phosphorylation Site Mutation in Human Fibroblast Growth Factor-1 Differentially Affects Mitogenic and Glucose-Lowering Activities. Xia X, Kumru OS, Blaber SI, Middaugh CR,…

  • Dr. Aaron DiAntonio October Publication

    NMNAT1 inhibits axon degeneration via blockade of SARM1-mediated NAD+ depletion. Sasaki Y, Nakagawa T, Mao X, DiAntonio A, Milbrandt J. Elife. 2016 Oct 13;5.

  • Drs. Jeanne Nerbonne and Stacey Rentschler New Publication

    Notch-Mediated Epigenetic Regulation of Voltage-Gated Potassium Currents. Khandekar A, Springer S, Wang W, Hicks S, Weinheimer CJ, Diaz-Trelles R, Nerbonne JM, Rentschler S. Circ Res. 2016…

  • Dr. Doug Covey December Publication

    TSPO activation modulates the effects of high pressure in a rat ex vivo glaucoma model. Ishikawa M, Yoshitomi T, Covey DF, Zorumski CF, Izumi Y.…

  • Dr. Kelly Monk November Publication

    G Protein-Coupled Receptors in Myelinating Glia. Mogha A, D'Rozario M, Monk KR.Trends Pharmacol Sci. 2016 Nov;37(11):977-987.

  • Dr. Andrew Yoo September Publication

    Maintenance of age in human neurons generated by microRNA-based neuronal conversion of fibroblasts. Huh CJ, Zhang B, Victor MB, Dahiya S, Batista LF, Horvath S,…

  • Dr. Kelly Monk September Publication

    Structural Basis for Regulation of GPR56/ADGRG1 by Its Alternatively Spliced Extracellular Domains. Salzman GS, Ackerman SD, Ding C, Koide A, Leon K, Luo R,…

  • Dr. Shim Imai September Publication

    NAMPT-Mediated NAD(+) Biosynthesis Is Essential for Vision In Mice. Lin JB, Kubota S, Ban N, Yoshida M, Santeford A, Sene A, Nakamura R, Zapata N,…

  • Dr. Kelly Monk August Publication

    The prion protein is an agonistic ligand of the G protein-coupled receptor Adgrg6. Küffer A, Lakkaraju AK, Mogha A, Petersen SC, Airich K,…

  • Dr. Doug Covey’s New Publication

    Development of a bile acid-based newborn screen for Niemann-Pick disease type C. Jiang X, Sidhu R, Mydock-McGrane L, Hsu FF, Covey DF, Scherrer DE, Earley…

  • Dr. Solnica-Krezel’s New Publication

    Dachsous1b cadherin regulates actin and microtubule cytoskeleton during early zebrafish embryogenesis. Li-Villarreal N, Forbes MM, Loza AJ, Chen J, Ma T, Helde K, Moens…

  • Dr. Jeanne Nerbonne’s New Publication

    IA Channels Encoded by Kv1.4 and Kv4.2 Regulate Circadian Period of PER2 Expression in the Suprachiasmatic Nucleus. Granados-Fuentes D, Hermanstyne TO, Carrasquillo Y, Nerbonne JM,…

  • Dr. David Ornitz’s New Publication

    Fibroblast growth factor signaling in skeletal development and disease. Ornitz DM, Marie PJ. Genes Dev. 2015 Jul 15;29(14):1463-86.

  • Dr. Snyder-Warwick’s New Publication

    Side-To-Side Nerve Bridges Support Donor Axon Regeneration Into Chronically Denervated Nerves and Are Associated With Characteristic Changes in Schwann Cell Phenotype.Hendry JM, Alvarez-Veronesi MC,…

  • Dr. Snyder-Warwick’s New Publication

    Maxillomandibular Fixation by Plastic Surgeons: Cost Analysis and Utilization of Resources. Farber SJ, Snyder-Warwick AK, Skolnick GB, Woo AS, Patel KB. Ann Plast Surg. 2015 Jul 23.

  • Dr. Lila Solnica-Krezel’s Recent Publication

    A dynamic intracellular distribution of Vangl2 accompanies cell polarization during zebrafish gastrulation. Roszko I, S Sepich D, Jessen JR, Chandrasekhar A, Solnica-Krezel L. Development. 2015 Jul 15;142(14):250…

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