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Washington University in St. Louis - School of Medicine
Department of Developmental Biology

Washington University Cores

The Core Research Facilities and Resources website helps investigators identify Washington University Core Facilities with services, expertise, or equipment that will enhance their research projects.

To access the university's cores, click here.

Below are some of the frequently used cores.

Bakewell NeuroImaging Laboratory, BNL

The Bakewell NeuroImaging Laboratory (BNIL) provides access to high-quality equipment and technical support for optical imaging, including confocal, multiphoton and low light microscopy. Our aim is to provide research users with accessible and adaptable imaging platforms. BNIL is available to the Washington University community. We are a member of the P30 Neuroscience Blueprint Core (NBC), which provides additional shared resources for interdisciplinary neuroscience research. Neuroscience Blueprint Core facilities are available to the Washington University Neuroscience community. BNIL has two Olympus multichannel confocals, a Zeiss multiphoton-confocal, a Lowlight Imaging workstation, an epi-fluorescence only CCD camera and a Metamorph offline image analysis workstation. Consultation with BNIL management is required before your initial scanning period.

Center for High Performance Computing

CHPC provides access to high performance computing resources, a broad spectrum of scientific computing software, and expert support to help faculty make use of deep computing resources. Usage is free to all faculty of Washington University.

Electron Microscopy Core

A full service transmission electron microscopy facility.

Embryonic Stem Cell (ESC) Core - Siteman Cancer Center

This core assists investigators in the Cancer Center with the generation of manipulated murine ES cells used to make sophisticated mouse models of human diseases, including cancer.

Flow Cytometry and Fluorescence Activated Cell Sorting

The Flow Cytometry Core provides investigators with instrumentation and support for cell sorting as well as acquisition and analysis of flow cytometry data.

Genome Technology Access Center (GTAC)

The Genome Technology Access Center (GTAC) provides DNA/RNA analysis resources for researchers at Washington University and beyond. We currently provide NextGen sequencing (2 illumina HiSeq2000s), microarray (all formats) and quantitative PCR.

High Throughput Screening Core

This core enables small molecule screens to identify agonists/antagonist of biologically/pathologically interesting proteins and perform sub- or genome-wide siRNA screens in live cell functional assays.

Hope Center Animal Surgery Cores

The Hope Center Animal Surgery Core provides technical support and conducts experiments employing rodent models of neurological diseases.

Hope Center Viral Vectors Core

The Hope Center Viral Vectors core provides lentiviral and AAV viral vectors for research applications. The Core provides traning and advice on vector usage and design and both small and large scale vector preprations.

Human Embryonic Stem Cell (hESC) Core

The hESC Core provides facilities, reagents, and resources for hESC use, data collection, and training.

Mouse Genetics Core

The Mission of the Mouse Genetics Core (MGC) is to provide a cost-effective method for generating and maintaining genetically altered mice for the entire Washington University research community.

PNACL DNA Sequencing Laboratories

The Protein Nucleic Acid Chemistry Laboratory (PNACL) at Washington University was established in 1984. The PNACL are multi-user shared instrumentation core laboratories that provide sophisticated capabilities that would not otherwise be available to individual researchers.  The Protein Nucleic Acid Chemistry Laboratory automated DNA sequencing using Applied
Biosystems Models 3130 and 3730 DNA sequencers.

In addition to performing analytical services, the Director and staff of the PNACL are available for consultation in experimental design, interpretation of data, and any other aspect in
which they can be of assistance.

Tissue Culture Support Center

We maintain a stockroom offering approximately 1500 commonly used lab consumables from more than 20 vendors which are available to the research community at a discount. Same day pickup or delivery is available for most products. We also provide basic tissue culture services and training in stem cell technology. We offer long-term cell storage, mycoplasma testing and provide access to various technologies requiring specialized equipment such as Amaxa's 4D Nucleofection device and Seahorse Bioscience's XF technology.

 

Upcoming Events

Mar 27

Iva Greenwald, PhD

Department of Developmental Biology Seminar Series

Professor of Biological Sciences Professor of Biochemistry and Molecular…

Mar 29

Margot Kossmann Williams (Solnica-Krezel Lab)/ Laura Arthur (Djuranovic Lab)

Development and Regenerative Biology / Cell-Cell Interactions in Cancer Research Forum (Wednesday)

12:00 pm, Needleman Library

Apr 3

Mark Mercola, PhD

Department of Developmental Biology Seminar Series

Professor of Medicine (Cardiovascular) Stanford School of Medicine 12:00 pm,…

See all upcoming events

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